過去の研究業績

2021 年
Validation of a self-report questionnaire for periodontitis in a Japanese population
Masanori Iwasaki ,Michihiko Usui, Wataru Ariyoshi, Keisuke Nakashima, Yoshie Nagai-Yoshioka, Maki Inoue, Kaoru Kobayashi, Wenche S. Borgnakke, George W. Taylor, Tatsuji Nishihara, Scientific Reports, 11(1), 15078, 2021.
Evaluation of the ability of the trypsin-like peptidase activity assay to detect severe periodontitis
Masanori Iwasaki ,Michihiko Usui, Wataru Ariyoshi, Keisuke Nakashima, Yoshie Nagai-Yoshioka, Maki Inoue, Kaoru Kobayashi, Tatsuji Nishihara, PLoS ONE, 2021, 16, e0256538
Magnesium Hydroxide Nanoparticles Kill Exponentially Growing and Persister Escherichia coli Cells by Causing Physical Damage
Yohei Nakamura, Kaede Okita, Daisuke Kudo, Dao Nguyen Duy Phuong, Yoshihito Iwamoto,Yoshie Yoshioka, Wataru Ariyoshi, Ryota Yamasaki, Nanomaterials, 11(6), 1584, 2021.
β-glucan suppresses cell death of ASC deficient macrophages invaded by periodontopathic bacteria through the caspase-11 pathway
Inoue, M., Okinaga, T., Usui, M., Kawano, A., Thongsiri, C., Nakashima, K., Ariyoshi, W., Nishihara, T, FEMS Microbiol Lett, 366 (8) pii: fnz093, 2019.
Biological Effects of β-Glucans on Osteoclastogenesis
Wataru Ariyoshi , Shiika Hara, Ayaka Koga, Yoshie Nagai-Yoshioka and Ryota Yamasaki, Molecules, 26, 1982, 2021.
Schizophyllum commune β-glucan: effect on interleukin-10 expression induced by lipopolysaccharide from periodontopathic bacteria
Chuencheewit Thongsiri; Yoshie Nagai-Yoshioka; Ryota Yamasaki; Yoshiyuki Adachi; Michihiko Usui; Keisuke Nakashima; Tatsuji Nishihara, Carbohydrate Polymers, 253(1), 117285, 2021.
Dectin‐1–mediated suppression of RANKL‐induced osteoclastogenesis by glucan from baker's yeast
Shiika Hara, Yoshie Nagai‐Yoshioka, Ryota Yamasaki, Yoshiyuki Adachi, Yuko Fujita, Kouji Watanabe, Kenshi Maki, Tatsuji Nishihara, Wataru Ariyoshi, Journal of Cellular Physiology, 236(7), 5098–5107, 2021.
Interruption of regular dental visits during the COVID-19 pandemic due to concerns regarding dental visits was associated with periodontitis in Japanese office workers
Masanori Iwasaki, Michihiko Usui, Wataru Ariyoshi, Keisuke Nakashima, Yoshie Nagai-Yoshioka, Maki Inoue, Kaoru Kobayashi, Tatsuji Nishihara, Journal of Periodontal Research, 2021.

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2020 年

Rhamnolipids and surfactin inhibit the growth or formation of oral bacterial biofilm

Ryota Yamasaki, Aki Kawano, Yoshie Yoshioka, Wataru Ariyoshi, BMC Microbiology, 20:358, 2020.

Hematogenous apoptotic mechanism in salivary glands in chronic periodontitis

Shikayama Y, Fujita-Yoshigaki J, Sago-Ito M, Nakamura-Kiyama M, Naniwa M, Hitomi S, Ujihara I, Kataoka S, Yada N, Ariyoshi W, Usui M, Nakashima K, Archives of Oral Biology, 117:104775, 2020.

3D Spheroid Culture Models for Chondrocytes Using Polyethylene Glycol-Coated Microfabricated Chip

Ariyoshi W, Usui M, Sano K, Kawano A, Okinaga T, Nakashima K, Nakazawa K, and Nishihara T, Biomedical Research (Tokyo), 41 (4): 187-197, 2020.

A Preliminary Study on the Ability of the Trypsin-Like Peptidase Activity Assay Kit to Detect Periodontitis

Iwasaki M, Usui M, Ariyoshi W, Nakashima K, Nagai-Yoshioka Y, Inoue M, Nishihara T, Dentistry Journal, 8 (3): E98, 2020.

Reactive oxygen species penetrate persister cell membranes of Escherichia coli for effective cell killing

Kawano, A., Yamasaki R., Sakakura, S., Takatsuji, Y., Haruyama, T., Yoshioka, Y., Ariyoshi, W., Front. Cell. Infect.  Microbiol., 10, 2020.

Docosahexaenoic acid attenuates cell death and interleukin-1β secretion in THP-1 cells responded to Aggregatibacter actinomycetemcomitans invasion

Aki Kawano, Wataru Ariyoshi, Ryota Yamasaki, Yoshie Yoshioka, Kosuke Kashiwagi, Daisuke Namikawa, Tatsuji Nishihara, Toshinori Okinaga, Biomedical Research, 31 (4): 93-100, 2020.

Persister Cells Resuscitate Using Membrane Sensors that Activate Chemotaxis, Lower cAMP Levels, and Revive Ribosomes

Yamasaki, R., Song, S., Benedik, M. J., Wood, T. K., iScience, 23(1), 100792, 2020.

Co-cultured spheroids of human periodontal ligament mesenchymal stem cells and vascular endothelial cells enhance periodontal tissue regeneration

Sano, K. Usui, M., Moritani, Y., Nakazawa, K., Hanatani, T., Kondo, H., Nakatomi, M., Onizuka, S., Iwata, T., Sato, T., Togari, A., Ariyoshi, W., Nishihara, T., Nakashima, K, Regen Ther, 14: 59-71, 2020.

Comparison of dental plaque reduction after use of electric toothbrushes with and without QLF-D-applied plaque visualization: a 1-week randomized controlled trial

Akifusa, S., Isobe, A., Kibata, K., Oyama, A., Oyama, H., Ariyoshi, W., Nishihara, T, BMC Oral Health, 20 (1): 4, 2020.

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2019年

Ameloblastin attenuates RANKL-mediated osteoclastogenesis by suppressing activation of nuclear factor of activated T cells cytoplasmic1 (NFATc1)

Chaweewannakorn, W., Ariyoshi, W., Okinaga, T., Fujita, Y., Maki, K., Nishihara, T, J Cell Physiol. 234: 1745-1757, 2019.

Anticancer effect of novel platinum nanocomposite beads on oral squamous cell carcinoma cells

Tanaka, M., Okinaga, T., Iwanaga, K., Matsuo, K., Toyono, T., Sasaguri, M., Ariyoshi, W., Tominaga, K., Enomoto, Y., Matsumura, Y., Nishihara, T, J Biomed Mater Res B, 107(7): 2281-2287, 2019.

Accumulation of hyaluronic acid in stromal cells modulates osteoclast formation by regulation of receptor activator of nuclear factor kappa-B ligand expression

Nakao., Y, Hikiji, H., Okinaga, T., Takeuchi, J., Manabu, H., Yoshiga, D., Yoshioka, I., Nishihara, T., Ariyoshi, W, Biochemi Biophys Res Commun, 512: 537-543, 2019.

The biological effects of Interleukin-17A on adhesion molecules expression and foam cell formation in atherosclerotic lesions

Shiotsugu, S., Okinaga, T., Habu, M., Yoshiga, D., Yoshioka, I., Nishihara, T., Ariyoshi W, J Interferon Cytokine Res, 39(11): 694-702, 2019.

Docosahexaenoic Acid Enhances M2 Macrophage Polarization via the p38 Signaling Pathway and Autophagy

Kawano, A., Ariyoshi, W., Yoshioka, Y., Hikiji, H., Nishihara, T., Okinaga, T, J Cell Biochem. 120: 12604-12617, 2019

β-glucan suppresses cell death of ASC deficient macrophages invaded by periodontopathic bacteria through the caspase-11 pathway

Inoue, M., Okinaga, T., Usui, M., Kawano, A., Thongsiri, C., Nakashima, K., Ariyoshi, W., Nishihara, T, FEMS Microbiol Lett, 366 (8) pii: fnz093, 2019.

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2018年

Ky-2, a hybrid compound histone deacetylase inhibitor, regulated inflammatory response in LPS-driven human macrophages

Kaneko, J., Okinaga, T., Ariyoshi, W., Hikiji, H., Fujii, S., Iwanaga, K., Tominaga, K., Nishihara, T., Cell Biol Int. 42 : 1622-1631, 2018.

​Zoledronic acid exacerbates inflammation through M1 macrophage polarization

Kaneko, J., Okinaga, T., Hikiji, H., Ariyoshi, W., Yoshiga, D., Habu, M., Tominaga, K., Nishihara., T. Inflammation Regenerat. 38:16, 2018.

Mechanisms involved in enhancement of osteoclast formation by activin-A

Kajita, T., Ariyoshi, W., Okinaga, T., Mitsugi, S., Tominaga, K., Nishihara, T. J Cell Biochem. 119: 6974-6985, 2018.

Spheroid culture enhances osteogenic potential of periodontal ligament mesenchymal stem cells

Moritani, Y., Usui, M., Sano, K., Nakazawa, K., Hanatani, T., Nakatomi, M., Sato, T., Ariyoshi, W., Nishihara, T., Nakashima, K.J Periodontal Res. 53: 870-882, 2018.